Dampak Pemberian Teh Daun Kelor (Moringa oleifera) terhadap Kadar Glukosa Darah pada Penderita Diabetes Melitus Tipe 2 di Wilayah Puskesmas Kecamatan Cakung, Jakarta Timur
Abstract
The content of epigallocatechin-3-gallate (EGCG) in moringa leaves which has antioxidant properties and acts as an antidiabetic can help lower blood glucose levels. This type of research is experimental, with a pretest-posttest control group design and a quantitative approach. Respondents in this study were 30 people, with 15 in the control group and 15 in the intervention group. Respondents must meet the inclusion criteria, namely suffering from type 2 diabetes mellitus according to data from the Cakung Sub-district health center, East Jakarta, aged 45 to 74 years having mild to moderate physical activity, and not suffering from complications and taking drugs from health workers. Respondents measured their initial blood glucose levels (pretest), then were given treatment by giving moringa leaf tea as much as 200 ml, after that the final blood glucose levels were measured (posttest). The decrease in blood glucose levels in the control group was 21.6 mg dL-1 and the decrease in blood glucose levels in the intervention group was 29.7 mg dL-1. Giving moringa leaf tea brewed in 200 ml of water can significantly impact blood glucose levels in patients with type 2 diabetes mellitus, which marks a decrease in blood glucose levels after treatment, with p-value < 0.05. There is a significant effect on reducing blood glucose levels in patients with type 2 diabetes mellitus with p-value < 0.05 after giving 200 ml of moringa leaf tea (p-value 0.01) so that it can be used as an alternative to lower blood glucose levels for diabetics.
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Al-Malki, A. L., & El Rabey, H. A. (2015). The antidiabetic effect of low doses of Moringa oleifera Lam. seeds on streptozotocin induced diabetes and diabetic nephropathy in male rats. BioMed Research International, 2015, 381040. https://doi.org/10.1155/2015/381040
American Diabetes Association. (2020). Classification and diagnosis of diabetes: Standards of medical care in diabetes-2020. Diabetes Care, 43(Supplement_1), S14–S31. https://doi.org/10.2337/dc20-S002
Chou, M. Y., Huang, S. T., Liang, C. K., Hsiao, F. Y., & Chen, L. K. (2020). Clinical characteristics and 10-year outcomes of diabetes in adults with advancing age at onset: A population cohort. Archives of Gerontology and Geriatrics, 88(201), 104039. https://doi.org/10.1016/j.archger.2020.104039
Fombang, E. N., & Saa, R. W. (2016). Antihyperglycemic activity of Moringa oleifera Lam. leaf functional tea in rat models and human subjects. Food and Nutrition Sciences, 7(11), 1021–1032. https://doi.org/10.4236/fns.2016.711099
Giridhari, V. V. A., Malathi, D., & Geetha, K. (2011). Anti diabetic property of drumstick (Moringa oleifera) leaf tablets. International Journal of Health & Nutrition, 2(1), 1–5. Tersedia dari https://moringatrees.org/moringa-doc/anti_diabetic_property_of_moringa_oleifera.pdf
Hilmi, A. A., & Budijastuti, W. (2021). Pengaruh pemberian senyawa epigallocatechine gallate (EGCG) terhadap penurunan kadar glukosa darah dan histopatologi testis mencit diabetes melitus induksi alloxan monohydrate. LenteraBio: Berkala Ilmiah Biologi, 9(2), 146–152. https://doi.org/10.26740/lenterabio.v9n2.p146-152
International Diabetes Federation. (2015). IDF diabetes atlas seventh edition. Tersedia dari https://www.diabetesatlas.org/upload/resources/previous/files/7/IDF%20Diabetes%20Atlas%207th.pdf
Jang, M. H., Piao, X. L., Kim, J. M., Kwon, S. W., & Park, J. H. (2008). Inhibition of cholinesterase and amyloid-β aggregation by resveratrol oligomers from Vitis amurensis. Phytotherapy Research, 22(4), 544–549. https://doi.org/10.1002/ptr.2406
Joeliantina, A. (2014). Pemeliharaan kadar glukosa darah. Jurnal Keperawatan, 7(1), 49–53. Tersedia dari http://journal.poltekkesdepkes-sby.ac.id/index.php/KEP/article/view/504
Krawczyk, M., Burzynska-Pedziwiatr, I., Wozniak, L. A., & Bukowiecka-Matusiak, M. (2022). Evidence from a systematic review and meta-analysis pointing to the antidiabetic effect of polyphenol-rich plant extracts from Gymnema montanum, Momordica charantia and Moringa oleifera. Molecular Biology, 44(2), 699–717. https://doi.org/10.3390/cimb44020049
Mereles, D., & Hunstein, W. (2011). Epigallocatechin-3-gallate (EGCG) for clinical trials: More pitfalls than promises? International Journal of Molecular Sciences, 12(9), 5592–5603. https://doi.org/10.3390/ijms12095592
Nintami, A. L., & Rustanti, N. (2012). Kadar serat, aktivitas antioksidan, amilosa, dan uji kesukaan mi basah dengan subtitusi tepung ubi jalar ungu (Ipomoea batatas var Ayamurasaki) bagi penderita diabetes melitus tipe-2. Journal of Nutrition College, 1(1), 382–387. https://doi.org/10.14710/jnc.v1i1.679
Pahlawati, A., & Nugroho, P. S. (2019). Hubungan tingkat pendidikan dan usia dengan kejadian diabetes melitus di wilayah kerja puskesmas Palaran Kota Samarinda tahun 2019. Borneo Student Research (BSR), 1(1), 1–5. Tersedia dari http://journals.umkt.ac.id/index.php/bsr/article/view/479
Peres, I., Rocha, S., Gomes, J., Morais, S., Pereira, M. C., & Coelho, M. (2011). Preservation of catechin antioxidant properties loaded in carbohydrate nanoparticles. Carbohydrate Polymers, 86(1), 147–153. https://doi.org/10.1016/j.carbpol.2011.04.029
Putri, N. L. (2014). Pengaruh pemberian teh daun kelor (Moringa oleifera) setelah dan sebelum terhadap glukosa darah post-pandrial dewasa sehat. Bogor: Institut Pertanian Bogor. Tersedia dari https://repository.ipb.ac.id/handle/123456789/74126
Radiansah, R., Rahman, N., & Nuryanti, S. (2013). Ekstrak daun kelor (Moringa oleifera) sebagai alternatif untuk menurunkan kadar gula darah pada mencit. Jurnal Akademika Kimia, 2(2), 54–61. Tersedia dari http://jurnal.untad.ac.id/jurnal/index.php/JAK/article/view/7726
Reswan, H., Alioes, Y., & Rita, R. S. (2017). Gambaran glukosa darah pada lansia di Panti Sosial Tresna. Jurnal Kesehatan Andalas, 6(3), 673–678. Tersedia dari https://scholar.google.com/scholar?hl=id&as_sdt=0%2C5&q=Gambaran+glukosa+darah+pada+lansia+di+Panti+Sosial+Tresna&btnG=
Ri, F., & Wirawanni, Y. (2012). Asupan energi, karbohidrat, serat, beban glikemik, latihan jasmani dan kadar gula darah pada pasien diabetes mellitus tipe 2. Media Medika Indoesiana, 46(2), 121–131. Tersedia dari https://ejournal.undip.ac.id/index.php/mmi/article/view/4273
Riset Kesehatan Dasar [Riskesdas]. (2018a). Hasil utama riset kesehatan dasar 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Tersedia dari https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf
Riset Kesehatan Dasar [Riskesdas]. (2018b). Laporan nasional riset kesehatan dasar 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Tersedia dari http://repository.litbang.kemkes.go.id/3514/
Rudi, A., & Kwureh, H. N. (2017). Faktor risiko yang mempengaruhi kadar gula darah puasa pada pengguna layanan laboratorium. Wawasan Kesehatan, 3(2), 33–39. https://doi.org/10.31227/osf.io/d3kes
Spadiene, A., Savickiene, N., Ivanauskas, L., Jakstas, V., Skesters, A., Silova, A., & Rodovicius, H. (2014). Antioxidant effects of Camellia sinensis L. extract in patients with type 2 diabetes. Journal of Food and Drug Analysis, 22(4), 505–511. https://doi.org/10.1016/j.jfda.2014.04.001
Suprapti, D. (2017). Hubungan pola makan karbohidrat, protein, lemak, dengan diabetes mellitus pada lansia. Jurnal Kebidanan, 1(1), 6–15. Tersedia dari Tersedia dari http://digilib.stikesicme-jbg.ac.id/ojs/index.php/jib/article/view/449
Vargas-Sánchez, K., Garay-Jaramillo, E., & González-Reyes, R. E. (2019). Effects of Moringa oleifera on glycaemia and insulin levels: A review of animal and human studies. Nutrients, 11(12), 1–19. https://doi.org/10.3390/nu11122907
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