Antioxidants Effectivity In Skin Lotion Formulation Of Mesocarp Fruit Extract Lontar (Borassus Flabellifer) Against White Rats Wistar Male In-Situ

Luthfiasari Amatullah, Tri Nur Cahyaningrum, Anisa Nur Fidyaningsih

Abstract

Study of bioactive mesocarp on palm fruits has been conducted previously. Therefore, this research aims to make a preparation of antioxidant skin lotion palm fruit mesocarp (Borrasus flabellifer) and to evaluate the effects of antioxidants on skin preparation lotion palm fruit (Borrasus flabellifer) by In-situ.

This study was an experimental study by making a preparation of skin lotion on the stability of the corresponding and testing the antioxidant treatment with a sample of 30 rats male wistar strain. The antioxidant test was divided into 5 groups randomly: negative control (-), positive control (compound sunscreen brands parasol SPF 33), group 1 (lotio extract palm fruit mesocarp with a concentration of 0.2%), group 2 (lotio palm fruit mesocarp extract with concentration of 0.4%) and group 3 (lotio palm fruit mesocarp extract with concentration 0.8%).

The results of in-situ states showed 0.8% extract of palm fruit mesocarp exhibited the least erythema score which was an average of 1.7. It was comparable to positive control which exhibited similar erythema score.

Full Text:

PDF

References

Aiache, J.M. (1993). Farmasetika 2 Biofarmasi. Edisi ke-2. Penerjemah: Dr. Widji Soeratri. Surabaya: Penerbit Airlangga University Press. Hal. 7thk http//www.Portalkalbe.com

Anonim,1998. Farmakope Indonesia Edisi III. Departemen kesehatan RI: jakarta.

Baumann, L & Allemann, IB 2009, Antioxidants. in: Baumann L, Saghari, S, Weisberg (eds). Cosmetic dermatology principles and practice, 2nd edn. New York: McGraw-Hill, pp. 292-311.

Dirjen POM. 1986. Sediaan Galenik Jilid II. Departemen Kesehatan RI: Jakarta.

Harbone, J.B. 1987. Metode Fitokimia Penuntun Cara Modern Menganalisa Tumbuhan. Terbitan kedua. Terjemahan Kosasih Padmawinata dan Iwang Soediro. Penerbit ITB: Bandung. 10

Lachman, L, Lieberman, H, A, dkk, 1994 Teori dan Praktek Farmasi Industri, Edisi III, Penerbit Universitas Indonesia, UI - Press, Jakarta.

Mitsui, T. (1997). New Cosmetic Science. Edisi Kesatu. Amsterdam: Elsevier Science.

Rieger, M.., 1994. Emulsion in Lachman, L., Lieberman, H.A., and Kanig, J.L., The Theory and Practice od Industrial Pharmacy. Lea & Febiger, Philadelphia, hal. 11029–1087.

Sibuea, P, 2003, Antioksidan Senyawa Ajaib Penangkal Penuaan Dini, Sinar Harapan, Yogyakarta

Silva,c,m,dkk,2006. Microencapsulation of hemoglobin in chitosan-coeted alginate micropheres prepared by emulsification internal gelation_AAPS JOURNAL 7:E903-E912

Voigt, R. 1995. Buku Pelajaran Teknologi Farmasi. UGM Press: Yogyakarta.

Wijayakusuma, Dalimarta. 1994. Tanaman Berkhasiat Obat di Indonesia. Jilid 2. Pustaka Kartini: Jakarta

DOI: https://doi.org/10.20961/jpscr.v2i1.5236

Refbacks

  • There are currently no refbacks.