Severe Weil's Disease Complicated by Symmetrical Peripheral Gangrene

Nurul Fitri Syarifah, Robert Satriyo Budi Susilo

Abstract

A man in his 70s presented with fever, jaundice, myalgia, and shortness of breath, which rapidly progressed to septic shock, acute kidney injury (AKI), and acute respiratory distress syndrome (ARDS). The diagnosis of Weil's disease was confirmed by a positive urine Polymerase Chain Reaction (PCR) for pathogenic Leptospira. A rare and severe complication of symmetrical peripheral gangrene developed in all four extremities. Intensive care management included mechanical ventilation, vasopressors, antibiotics, and hemodialysis. Despite initial stabilization and confirmation of the underlying infection, the patient's condition ultimately deteriorated, leading to his death on the 25th day of hospitalization. This case highlights symmetrical peripheral gangrene as a devastating vascular complication of severe leptospirosis and underscores the importance of early, aggressive, multidisciplinary management.

Keywords

Acute Kidney Injury; Gangrene; Leptospirosis; Sepsis; Weil Disease

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References

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DOI: https://doi.org/10.20961/tscm.v3i1.115145

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