Potency of green chiretta (Andrographis paniculata) leaf extract on antibody titers of laying chickens in the starter phase

Abstract

Objective: Andrographolide, a bioactive compound found in Green chiretta (Andrographis paniculata), as an immunomodulator and feed additive for laying hens, has been potential to be explored. This experiment aims to determine the effect of green chiretta (Andrographis paniculata) leaf extract on antibody titers of Avian Influenza (AI) and Newcastle Disease (ND) of starter phase laying hens.

Methods: 100 Isa Brown strain laying hens were used. The cages used were 20 box cages of 60x50x50 cm. The research method used is a completely randomized design (CRD) with 5 treatments T0 = Drinking water without EEGC, T1 = Drinking water + 0.5% EEGC, T3 = Drinking water + 1% EEGC, T4 = Drinking water + 1.5% EEGC, T5 = Drinking water + 2% EEGC. Each treatment was repeated 4 times.

Results: The result of the analysis of variance showed that the treatment of green chiretta leaf extract had no significant effect on AI and ND antibody titers at 3, 4, and 5 weeks of age but had a significant effect on AI and ND antibody titers at 6 weeks

Conclusions: The supplementation of green chiretta (Andrographis paniculata) leaf extract in drinking water accelerated the formation of AI and ND antibody titers. It was able to maintain higher antibodies compared to the control treatment. The supplementation of green chiretta (Andrographis paniculata) leaf extract in drinking water maintained AI and ND antibody titers.