Relation of NLR Value and Mortality Rate in Neonatal Sepsis

Jarwoto Roestanajie, Muhammad Ali Shodikin

Abstract

Introduction: Neonatal sepsis is a significant issue for newborns everywhere and causes a large amount of morbidity and mortality. Various indicators of newborn sepsis are expensive and occasionally unavailable in peripheral hospitals. The neutrophil-lymphocyte ratio (NLR), which is affordable, is a component of complete blood counts and does not call for further testing. This study intended to investigate the neutrophil-to-lymphocyte ratio (NLR) as a predictor of neonatal mortality rate in the local hospital in rural locations.

Methods: This study sampled newborns with sepsis in the perinatal room of dr. Soebandi Hospital Jember for this cross-sectional study, from January 2021 to June 2022. NLR is calculated by manually dividing the number of neutrophils by the actual number of lymphocytes. Our neutrophil and lymphocyte data were obtained from the patient's lab results. This study analyzed neonatal sepsis NLR data using Spearman analysis to find the relation between NLR value and mortality rate of neonatal sepsis.

Results: This study obtained 43 data on neonatal sepsis in the perinatology ward during this period. The data found to show that 37 neonatal sepsis survived and 6 died. The collected data analysis found that the lowest NLR neonatal sepsis is 0.4, the highest NLR neonatal sepsis is 25.6 and the mean value for NLR neonatal sepsis in perinatology was 3.88. This study found no correlation between the NLR value of the sepsis neonate and the neonatal mortality rate Sig. (2-tailed) 0.662.

Conclusion: In this study demonstrated no correlation between the NLR value of the sepsis neonates and the neonatal mortality rate.

Keywords

lymphocytes; mortality; neonatal sepsis; neutrophils

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References

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DOI: https://doi.org/10.13057/smj.v6i1.67343

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