Telusur Infeksi Tuberkulosis Laten pada Populasi Berisiko dan Investigasi Kontak pada Lingkup Puskesmas Gajahan Surakarta

Hendrastutik Apriningsih, Brigitta Devi Anindita Hapsari, Sihsusetyaningtyas Tiominar Siregar, Nurhasan Agung Prabowo, Desy Puspa Putri, Debby Andina Landiasari, Farahdila Mirshanti, Yunita ., Cahyani Fahmiati

Abstract

Pendahuluan: Indonesia merupakan salah satu dari negara dengan beban Tuberkulosis (TB) tertinggi di dunia. Penemuan Infeksi TB laten (ITBL) dan pemberian Terapi Pencegahan Tuberkulosis (TPT) merupakan salah satu strategi dalam upaya menurunkan beban TB nasional. Program Penanggulangan TB merubah strategi penemuan pasien TB aktif secara intensif dan masif berbasis keluarga dan Masyarakat. Pelacakan populasi berisiko dan investigasi kontak memiliki peran penting pada strategi ini. Diagnosis ITBL saat ini menggunakan Tuberculin Skin Test (TST) atau Interferon Gamma-Release Assay (IGRA). Metode: Tujuan kegiatan pengabdian ini untuk memberikan penyuluham mengenai ITBL dan pemberian TPT, serta peningkatan penemuan kasus ITBL pada investigasi kontak dan populasi berisiko yaitu pasien Diabetes Melitus (DM) di lingkup Puskesmas Gajahan Surakarta. Dilakukan pre-test dan post-test untuk evaluasi kegiatan penyuluhan tersebut.

Hasil dan pembahasan: Pemeriksaan tes tuberkulin pada 26 responden IK didapatkan 11 responden dengan hasil positif (42,3%) dan 25 responden dengan penyakit komorbid DM didapatkan 10 responden (40,0%) hasil positif.

Kesimpulan: Kegiatan telusur ITBL pada investigasi kontak dan populasi DM sangat diperlukan untuk membantu penurunan angka kejadian TB aktif.

Keywords

infeksi TB laten; investigasi kontak; diabetes mellitus; TST

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References

  1. Liu Q, Yan W, Liu R, Bo E, Liu J, Liu M. The Association Between Diabetes Melitus and the Risk of Latent Tuberculosis Infection: A Systematic Review and Meta-Analysis. Front Med 2022;9:1–10. https://doi.org/10.3389/fmed.2022.899821.
  2. Velen K, Shingde RV, Ho J, Fox GJ. The effectiveness of contact investigation among contacts of tuberculosis patients: A systematic review and meta-analysis. Eur Respir J 2021;58. https://doi.org/10.1183/13993003.00266-2021.
  3. Chaw L, Hamid RA, Koh KS, Thu K. Contact investigation of tuberculosis in Brunei Darussalam: Evaluation and risk factor analysis. BMJ Open Respir Res 2022;9:1–10. https://doi.org/10.1136/bmjresp-2022-001224.
  4. Ghanaiee RM, Karimi A, Hoseini-Alfatemi SM, Seddon JA, Nasehi M, Tabarsi P, et al. Household contact investigation for the detection of active tuberculosis and latent tuberculosis: A comprehensive evaluation in two high-burden provinces in Iran. New Microbes New Infect 2022;45:100958. https://doi.org/10.1016/j.nmni.2022.100958.
  5. Tepekule B, Kusejko K, Zeeb M, Tarr PE, Calmy A, Battegay M, et al. Impact of Latent Tuberculosis on Diabetes. J Infect Dis 2022;225:2229–34. https://doi.org/10.1093/infdis/jiac054.
  6. Abdul-Ghani R, Al-Awadi A, Al-aghbari N, Al-Mikhlafy AA, Abdulmoghni SS, Al-dobai SS, et al. Latent tuberculosis infection and diagnostic performance of the tuberculin skin test among type 2 diabetics in Sana’a city, Yemen. BMC Infect Dis 2024;24. https://doi.org/10.1186/s12879-024-09931-8.
  7. Goroh MMD, van den Boogaard CHA, Lukman KA, Lowbridge C, Juin WK, William T, et al. Factors affecting implementation of tuberculosis contact investigation and tuberculosis preventive therapy among children in Sabah, East Malaysia: A qualitative study. PLoS One 2023;18:1–16. https://doi.org/10.1371/journal.pone.0285534.
  8. Kumar NP, Babu S. Impact of diabetes melitus on immunity to latent tuberculosis infection. Front Clin Diabetes Healthc 2023;4:1–7. https://doi.org/10.3389/fcdhc.2023.1095467.
  9. Rea E, Huard J, Lee R. Chapter 11: Tuberculosis contact investigation and outbreak management. Can J Respir Crit Care, Sleep Med 2022;6:167–83. https://doi.org/10.1080/24745332.2022.2037909.
  10. Lung T, Marks GB, Nhung NV, Anh NT, Hoa NLP, Anh LTN, et al. Household contact investigation for the detection of tuberculosis in Vietnam: economic evaluation of a cluster-randomised trial. Lancet Glob Heal 2019;7:e376–84. https://doi.org/10.1016/S2214-109X(18)30520-5.
  11. Zhou G, Guo X, Cai S, Zhang Y, Zhou Y, Long R, et al. Diabetes melitus and latent tuberculosis infection: an updated meta-analysis and systematic review. BMC Infect Dis 2023;23:1–11. https://doi.org/10.1186/s12879-023-08775-y.
  12. Kemenkes RI. Strategi Nasional Penanggulangan Tuberkulosis di Indonesia 2020-2024. Pertem Konsolidasi Nas Penyusunan STRANAS TB 2020:135.
  13. Lin CH, Kuo SC, Hsieh MC, Ho SY, Su IJ, Lin SH, et al. Effect of diabetes melitus on risk of latent TB infection in a high TB incidence area: A community-based study in Taiwan. BMJ Open 2019;9:1–8. https://doi.org/10.1136/bmjopen-2019-029948.
  14. Ping PA, Zakaria R, Islam MA, Yaacob LH, Muhamad R, Mohamad WMZW, et al. Prevalence and risk factors of latent tuberculosis infection (LTBI) in patients with type 2 diabetes melitus (T2DM). Int J Environ Res Public Health 2021;18:1–8. https://doi.org/10.3390/ijerph18010305.

DOI: https://doi.org/10.20961/ssej.v5i3.105855

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