Clinical Characteristics of Hemodialysis Chronic Kidney Disease Patients at Sebelas Maret University Hospital

Muhammad Septian Surgebrama, Evi Liliek Wulandari, Lukman Aryoseto, Nurhasan Agung Prabowo

Abstract

Introduction: Chronic Kidney Disease (CKD) is a kidney function disorder lasting ≥3 months with a Glomerular Filtration Rate (GFR) <60 mL/min/1.73m².. Hemodialysis is the main therapy for end-stage CKD to replace kidney function, alleviate uremic symptoms, and improve patients’ quality of life, although it does not restore kidney function. Data on the characteristics of CKD patients undergoing hemodialysis, particularly in the Solo Raya region, are still limited, hence this study was conducted.

Methods: This descriptive study employed a retrospective approach using medical record data of CKD patients undergoing hemodialysis. A total of 82 patients were included using total sampling. Data were analyzed descriptively to describe characteristics based on age, genders, hemoglobin levels, duration of hemodialysis, body mass index (BMI), and etiology.

Results: CKD patients undergoing hemodialysis were predominantly aged 55–64 years and male. Most patients experienced anemia with hemoglobin levels <13 g/dL in males and <12 g/dL in females. The majority had undergone hemodialysis for more than 12 months, with the most common BMI category being normal. The most frequent etiology was hypertension.

Conclusion: CKD patients undergoing hemodialysis at Universitas Sebelas Maret Hospital were predominantly aged 55–64 years, male, experienced anemia, had undergone hemodialysis for more than 12 months, had a normal BMI, and hypertension as the most frequent etiology.

Keywords

chronic kidney disease; hemodialysis; hypertension; anemia; body mass index.

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References

  1. Kalra, P.A. Hypertension and the kidneys. British Journal of Hospital Medicine. 2022;83(5):1-11.
  2. Guppy, O., et al. Rate of decline in kidney function with age: a systematic review. BMJ Open. 2024;14(11):e089783.
  3. Kementerian Kesehatan Republik Indonesia. Laporan Nasional Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019.
  4. Tang, Y., et al. Global prevalence of frailty in hemodialysis patients: a systematic review and meta-analysis. Frontiers in Medicine. 2024;11:1722657.
  5. Shankar, M., Sankarasubaiyan, S., Kasiviswanathan, S., Shah, K.D., Luyckx, V. Gender Disparity in Hemodialysis Practices and Mortality: A Nationwide Cross-Sectional Observational Study. Indian J Nephrol. 2024;34(6):609-616.
  6. Jyothindrakumar, J., George, J.S., Thomas, E.A., Shameer, A.M., Hareesh, K.G., Manuel, S. WCN25-2897 Gender Inequality and Its Impact on Quality of Life Among Females on Hemodialysis in Kerala, India. Kidney Int Rep. 2025;10(2):S424-S425.
  7. Tong, A., Evangelidis, N., Kurnikowski, A., Lewandowski, M., Bretschneider, P., Oberbauer, R., et al. Nephrologists’ perspectives on gender disparities in ckd and dialysis. Kidney Int Rep. 2022;7(3):424-435.
  8. Prasetyo, A., Pranowo, S., Handayani, N. Karakteristik pasien gagal ginjal yang menjalani terapi hemodialisa di rsud cilacap. STIKes Bakti Tunas Husada Tasikmalaya; 2018.
  9. Hong, S.H., Lee, S. The Link between Body Mass Index and Mortality in Hemodialysis Patients. J Ren Nutr. 2019.
  10. Rabbani, R., Noel, E., Boyle, S., Khan, W.A., Pronovost, P., Gillespie, A. Impact of extremes of body mass index (bmi) in end-stage renal disease (esrd) patients. Cureus. 2022;14(6):e25892.
  11. Sitompul, F., et al. Gangguan cemas pada pasien penyakit ginjal kronik yang menjalani hemodialisis. e-Journal Keperawatan (e-Kp). 2023;11(2).
  12. Euphora, N.L., Samira, J. Hubungan lama menjalani hemodialisis dengan status gizi pada pasien gagal ginjal kronik. Indonesian Journal of Applied Science and Technology. 2023;4(1):96-107.
  13. Ruperto, M., Barril, G. Clinical significance of nutritional status, inflammation, and body composition in elderly hemodialysis patients: A case control study. Nutrients. 2023;15(24):5036.
  14. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 Clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2024;105(4S):S117-S314.
  15. Babitt, J.L., Lin, H.Y. Mechanisms of anemia in CKD. J Am Soc Nephrol. 2012;23(10):1631-4.
  16. WHO. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Geneva: World Health Organization; 2011.
  17. Putri, S.A., et al. Gambaran kejadian anemia pada remaja. Jurnal Ilmiah Kesehatan. 2022.
  18. Ariani, M.K., Adyan, A. Hubungan antara kejadian anemia dengan status gizi pada remaja putri: A systematic review. Sinar Jurnal Kebidanan. 2023;5(2).
  19. WHO. Global anaemia estimates, 2021 edition. Geneva: World Health Organization; 2021.
  20. Camaschella, C. Iron-deficiency anemia. N Engl J Med. 2015;372(19):1832-1843.
  21. McLean, E., et al. Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005. Public Health Nutrition. 2009;12(4):444-454.
  22. Smith, A., Jones, B. Gender differences in anemia among chronic kidney disease patients: a systematic review. Journal of Nephrology Research. 2021;8(2):45-56.
  23. Wang, L., et al. Erythropoietin Non-hematopoietic Tissue Response and Regulation of Metabolism During Diet-Induced Obesity. Frontiers in Endocrinology. 2020.
  24. Fan, X., et al. Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α. Oncotarget. 2017;8(10):16584–16596.
  25. Pencina, K.M., Travison, T.G., Artz, A.S., Lincoff, A.M., Nissen, S.E., Flevaris, P., et al. Efficacy of testosterone replacement therapy in correcting anemia in men with hypogonadism: A randomized clinical trial. JAMA Netw Open. 2023;6(10):e2340030.
  26. Sharma, A., et al. Testosterone-induced erythrocytosis. Clin Endocrinol (Oxf). 2022.
  27. Zhang, Y., Liu, W. Sex hormones and erythropoiesis: Understanding gender differences in hemoglobin concentration. BMC Hematology. 2024;24(2):55-63.
  28. Tahir, N.C., Rijal, S., Musa, I.M., Hidayati, P.H., Hamzah, P.N. Karakteristik pasien penyakit ginjal kronik yang menjalani terapi hemodialisis tahun 2019-2022 RSUD Prof. Dr .H. Aloe Saboe Gorontalo. Journal Of Spcial Science Research. 2022;4(1):9282-9294.
  29. Barzegar, H., Jafari, H., Charati, J.Y., Esmaeili, R. Relationship between duration of dialysis and quality of life in hemodialysis patients. Iranian Journal of Psychiatry and Behavioral Sciences. 2017;11(4):1-6.
  30. Rosa, D., Furqoni, P.D., Wardiyah, A. Hubungan lama menjalani hemodialisa (hd) dengan harga diri pada pasen gagal ginjal kronik di rumah sakit bintang amin bandar lampung. Mahalayati Nursing Journal. 2025;7(5):1905-1919.
  31. Lichtnekert, J., Anders, H.J. Lupus nephritis-related chronic kidney disease. Nature Reviews Rheumatology. 2024;20(11):699-711.
  32. Yu, A.S.L., Shen, C., Landsittel, D.P., Grantham, J.J., Cook, L.T., Torres, V.E., et al. Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease. Kidney International. 2019;95(5):1253–1261.
  33. De Bhailis, A.M., Kalra, P.A. Hypertension and the kidneys. British Journal of Hospital Medicine. 2022;83(5):1-11.

DOI: https://doi.org/10.20961/tscm.v3i4.111676

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