Determination of absorbed dose of Palladium-103 radiation sources in prostate brachytherapy using the Monte Carlo method

Mukhtar Effendi, Hafsyah Putri Nabila, wihantoro wihantoro, Aris Haryadi

Abstract

Prostate cancer is one type of cancer that can be treated with the Brachytherapy Technique. Brachytherapy is a cancer therapy method by implanting radioactive nuclei through electromagnetic radiation from radioactive material placed near the tumor or cancer. The optimal number of implants of Palladium-103 radioactive source needs to be known to ensure the safety level before performing the therapy. The stages carried out in the research include modeling radiation sources and inhomogeneous phantoms around cancer, running the program, and processing the running data. The value of radiation absorbed dose based on the interaction of photons on organs can be obtained using the tally code *f8 in the MCNPX user code input. Based on the research results, the absorbed dose value received by each organ was successfully obtained. In addition, the variation of the implanted Palladium-103 radiation source had a significant effect on the increase of absorbed dose received by each organ. Sources were varied as 10, 11, 12, 13, 14, 15, and 16 sources, respectively. The greater the number of radiation sources implanted, the greater the absorbed dose value received by each organ.

Keywords

cancer treatment; absorbed dose; prostate brachytherapy; palladium-103; MCNPX

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References

Akman. F., Ogul, H., Kaçal, M. R., Polat, H., Dilsiz, K. and Turhan. M. F. (2020), “Impact of lead(II) iodide on radiation shielding properties of polyester composites,” Appl. Phys. A Mater. Sci. Process., vol. 126, no. 4, pp. 1–9.

Effendi, M., Fatimah, R. U., Sholeh, A., and Fatchurohmah, W., (2019), “Design of the aluminum compensating filter to improve the image quality in the lateral projection of lumbosacral vertebrae,” AIP Conf. Proc., vol. 2094, no. April.

Effendi, M., Anindhita, T., Fatchurohmah, W., and Sholeh, A., (2022), “The effects of the operating voltage and source image distance of X-ray device on the absorption dosage and the improvement of the image for abdomen object,” AIP Conf. Proc., vol. 2391, no. March.

Farmer, J., and Roy, S., (2020), “A quasi-Monte Carlo solver for thermal radiation in participating media: A QMC solver for thermal radiation in participating media,” J. Quant. Spectrosc. Radiat. Transf., vol. 242, p. 106753.

Gaikwad, D.K., et al. (2019), “Physical, structural, optical investigation and shielding features of tungsten bismuth tellurite based glasses,” J. Non. Cryst. Solids, vol. 503–504, no. July, pp. 158–168.

Lazarine, D. A. (2006). Medical Physics Calculations With MCNPTM: A Primer. Texas: Texas A&M University.

More, C. V., Alsayed, Z., Badawi, M.S., Thabet, A. A., and Pawar, P. P. (2021), Polymeric composite materials for radiation shielding: a review, vol. 19, no. 3. Springer International Publishing.

Morton. (2015). Prostate high-doe-rate brachytherapy, transrectal ultrasound-based planning. 5-40.

Novák, J., Georgiev, I., Hanika, J., and Jarosz, W., (2018), “Monte Carlo methods for volumetric light transport simulation,” Comput. Graph. Forum, vol. 37, no. 2, pp. 551–576.

Palluotto, L., Dumont, N., Rodrigues, P.. Gicquel, O., and Vicquelin, R., (2019), “Assessment of randomized Quasi-Monte Carlo method efficiency in radiative heat transfer simulations,” J. Quant. Spectrosc. Radiat. Transf., vol. 236, p. 106570, 2019.

Rianaris, A. (2011). Simulasi Penentuan Dosis Serapan Pada Brachytherapy Prostat Menggunakan Software MCNP5. Surakarta: Universitas Negeri Surakarta.

Setiawan, P., Suharyana, & Riyatun. (2015). Simulasi Pengukuran Dosis Serap Pada Brachytherapy Prostat Berjari-Jari 2 CM Menggunakan Software MCNP5 Dengan Model Seed Implant ISOAID ADVANTAGETM IAPD-103A. Jurnal Fisika, 82-85.

Song, C.W., et al. (2021), “Biological Principles of Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiation Surgery (SRS): Indirect Cell Death,” Int. J. Radiat. Oncol. Biol. Phys., vol. 110, no. 1, pp. 21–34.

Sowards, K. (2007). Monte Carlo Dosimetric Characterization of the IsoAid ADVANTAGE 103Pd Brachytherapy Source. J.Appl.CLin.Med phys, 18-25.

Sujarweni, V. W. (2015). Metodologi Penelitian Bisnis Dan Ekonomi. Yogyakarta: Pustaka Baru Press.

Tekin, H.O., et al., (2020), “Sodium dodecatungs to phosphate hydrate-filled polymer composites for nuclear radiation shielding,” Mater. Chem. Phys., vol. 256, no. July, p. 123667.

Tuğrul, T., and Eroğul, O., (2019), “Determination of initial electron parameters by means of Monte Carlo simulations for the Siemens Artiste Linac 6 MV photon beam,” Reports Pract. Oncol. Radiother., vol. 24, no. 4, pp. 331–337.

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