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Erector Spinae Block vs Paravertebral Block in Breast Cancer Surgery: A Systematic Review and Meta-analysis


 
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1. Title Title of document Erector Spinae Block vs Paravertebral Block in Breast Cancer Surgery: A Systematic Review and Meta-analysis
 
2. Creator Author's name, affiliation, country Rizky Rahmad Tri Cahyo; Resident anesthesiology and intensive care, Diponegoro University; Indonesia
 
2. Creator Author's name, affiliation, country Doso Sutiyono; Anesthesiologist in Dr. Kariadi General Hospital Medical Center and Diponegoro University; Indonesia
 
2. Creator Author's name, affiliation, country Intan Karmila; Internship Doctor at Praya Regional Hospital, West Nusa Tenggara; Indonesia
 
2. Creator Author's name, affiliation, country Ismini Aufakamilia; Internship Doctor at Islamic Hospital Yatofa, West Nusa Tenggara; Indonesia
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Breast cancer surgery; Erector Spinae Plane Block (ESPB); Mastectomy; Paravertebral Block (PVB); Radical mastectomy.
 
4. Description Abstract  Background :The paravertebral block (PVB) is the gold standard for postoperative analgesia in breast surgery, but it easily causes pneumothorax. Erector spinae plane block (ESPB) is considered as alternative to PVB because its less invasive so relative safer. However, evidence in favor of these techniques is lacking. Method :A search of PubMed Central, Cochrane Library, Wiley Online Library, and ClinicalTrials.gov to identify the latest 20 years studies comparing ESPB and PVB in breast cancer surgery was conducted. Our endpoints were: intraoperative fentanyl consumption, total postoperative morphine, and time to first analgesic request. Result :A total of 6 studies (394 patients) were included for this meta-analysis. The pooled analysis showed there is -3.03 (MD = -3.03: 95% CI: -7.47– 1.42) mean difference with insignificant overall effect (P = 0.18) for intraoperative fentanyl consumption on ESPB patient after breast cancer surgery compared against PVB procedure. There is an insignificant between ESPB and PVB regarding total postoperative morphine with 0.46 (MD = 0.46: 95% CI: -0.94 – 1.85) mean difference with insignificant overall effect (P =0.52). There is a significant difference between ESPB and PVB regarding time to first analgesic request with 0.23(MD = 0.23: 95% CI: 0.01– 0.44) risk ratio with statistically significant overall effect (P = 0.04). Both intraoperative fentanyl consumption and total postoperative morphine consumption showed heterogeneity. Meanwhile, time to the first analgesic request showed no heterogeneity. Conclusion : PVB is superior to ESPB regarding time to first analgesic request, but ESPB can serve as an
alternative to PVB with a similar analgesic effect   
 
5. Publisher Organizing agency, location Fakultas Kedokteran Universitas Sebelas Maret Surakarta
 
6. Contributor Sponsor(s) Doso Sutiyono, 2Anesthesiologist in Dr. Kariadi General Hospital Medical Center and Diponegoro University; Intan Karmila, Internship Doctor at Praya Regional Hospital, West Nusa Tenggara; Ismini Aufa Kamilia, Internship Doctor at Islamic Hospital Yatofa.
 
7. Date (YYYY-MM-DD) 2025-10-31
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://jurnal.uns.ac.id/SOJA/article/view/67351
 
10. Identifier Digital Object Identifier https://doi.org/10.20961/soja.v5i2.67351
 
11. Source Title; vol., no. (year) Solo Journal of Anesthesi, Pain and Critical Care (SOJA); Vol 5, No 2 (2025): October 2025
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2025 Rizky Rahmad Tri Cahyo, Doso Sutiyono, Intan Karmila, Ismini Aufakamilia
https://creativecommons.org/licenses/by/4.0/